Eva M. SEVICK-MURACA,Caroline E. FIFE,Milton V. MARSHALL,Erik A. MAUS,John C. RASMUSSEN,I-Chih TAN
申请号：
US14818571
公开号：
US20160029948A1
申请日:
2015.08.05
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Methods and imaging agents are used to functionally image lymph structures and to identify, diagnose, assess, monitor and direct therapies for lymphatic disorders. Embodiments of the methods utilize highly sensitive optical imaging and fluorescent spectroscopy techniques capable of rapid temporal resolution to non-invasively track or monitor packets of imaging agents flowing in one or more lymphatic structures in human patients to provide quantitative information regarding lymph propulsion and functionality of the lymphatic structures. An imaging agent comprises a fluorophore labeled peptide capable of binding integrin α9β1 on a lymphatic structure.
