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Service induced byproducts for localized drug delivery in orthopaedic implants
专利权人:
John D. DesJardins
发明人:
John D. DesJardins,Martine LaBerge,Cassandra Wright-Walker
申请号:
US13360020
公开号:
US08858979B1
申请日:
2012.01.27
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A composite material including ultra-high molecular weight polyethylene in conjunction with a biologically active agent is described. The biologically active agent can be, for example, an anti-osteolytic agent such as a bisphosphonate. The composite material can be utilized in forming implants such as total joint replacement implants. The biologically active agent can be released from the composite material either from the bulk or from wear particles released from the surface of the implant component during use. Upon release, the biologically active agent can carry out the intended function of the agent.
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