A hand-held device for collecting a tissue sample comprising a needle mechanism and an operating mechanism, the needle mechanism comprising a cutting needle and a sample collecting needle, the needle mechanism being a first end for insertion into the tissue The cutting needle has a cutting edge for cutting the tissue specimen from the tissue, the sampling needle has a lateral opening for receiving the tissue, and the operating mechanism is a vacuum in fluid communication with the sampling needle A vacuum chamber comprising a first member and a second member, wherein the first and second members are adapted to move relative to each other, the first member being Mechanically coupled to the cutting needle, the handheld device increases the volume of the vacuum chamber and provides movement between the first member and the second member to reduce the pressure in the sampling needle. The cutting needle and the sampling needle to expose the lateral opening of the sampling needle And it is configured to cause movement.針機構と操作機構とを備える、組織標本の採取のための手持ち型装置であって、針機構は切断針と標本採取針とを備え、針機構は組織内に挿入するための第１の端部を有し、切断針は組織から組織標本を切断するための切れ刃を備え、標本採取針は組織を受け入れるための側方開口を備え、操作機構は標本採取針と流体連通している真空チャンバを備え、真空チャンバは第１の部材と第２の部材とを備え、第１および第２の部材は、互いに対して相対的に移動するように適合させられており、第１の部材は切断針に機械的に連結されており、手持ち型装置は、真空チャンバの体積を増大させ、標本採取針内の圧力を低下させるための第１の部材と第２の部材との間の動きが、標本採取針の側方開口を露出させるための切断針と標本採取針との間の動きを生じさせるように構成されている。
