TRPM8 ANTAGONISTS

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专利权人:

DOMPÉ FARMACEUTICI S.P.A.

发明人:

MORICONI, ALESSIO,BIANCHINI, GIANLUCA,COLAGIOIA, SANDRO,BRANDOLINI, LAURA,ARAMINI, ANDREA,LIBERATI, CHIARA,BOVOLENTA, SILVIA

申请号：

RSP20180793

公开号：

RS57389B1

申请日:

2012.12.19

申请国别(地区):

RS

年份:

2018

代理人:

摘要：

The invention relates to compounds acting as selective antagonists of Transient Receptor Potential cation channel subfamily M member 8 (TRPM8), and having formula (I). Said compounds are useful in the treatment of diseases associated with activity of TRPM8 such as pain, inflammation, ischaemia, neurodegeneration, stroke, psychiatric disorders, itch, irritable bowel diseases, cold induced and/or exhacerbated respiratory disorders and urological disorders.

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