The invention relates to describe host-specific extracellular phytotoxins produced by Fusarium sp. That has a phytotoxic to Lantana camara. A novel method using phytotoxin has been developed for controlling Lantana camara, these phytotoxin can be used partially pure, as a cell- and spore-free filtrate, a crude filtrate, or a crude suspension of the culture and optionally along with other additives. 18s rRNAsequence analysis showed 93% nucleotide similarity of the Fungi to Fusarium sp. But also indicated nucleotide variation of this fungus from other known genus of Nectaria, Mariannaea, Volutella, Myrothecium. This analysis suggested that the novel fungus is closest to Fusarium sp. It is proposed that this is a new species of Fusarium sp.