TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION
发明人:
SHIINA, ISAMU,SANO, YOSHIYUKI,NAKATA, KENYA
申请号：
EP07707418
公开号：
EP1982981A4
申请日:
2007.01.25
申请国别(地区):
EP
年份:
2012
代理人:
摘要：
Disclosed is a novel process for production of lasofoxifene, nafoxidine or an analogue thereof, which comprises reduced number of reaction steps, has a high efficiency, and is practically advantageous. For the production of lasofoxifene or an analogue thereof, a compound represented by the formula (4) is used as an intermediate. The compound represented by the formula (4) can be produced using compounds represented by the formulae (1) to (3) as starting compounds by performing the coupling of the three components in one step.
