Icahn School of Medicine at Mount Sinai;The Trustees Of Princeton University;École Normale Supérieure
发明人:
申请号：
EP16750061.0
公开号：
EP3256608A4
申请日:
2016.02.16
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
The present invention relates to a composition comprising an isolated, single stranded RNA molecule having a nucleotide sequence comprising 20 or more bases and a pattern of CpG dinucleotides defined by a strength of statistical bias greater than or equal to zero, and a pharmaceutically acceptable carrier suitable for injection. The present invention also relates to a kit comprising a cancer vaccine and the composition of the present invention as an adjuvant to the cancer vaccine. The present invention further relates to a method of treating a subject for a tumor and a method of stimulating an immune response.
