Solid forms of a selective cdk4/6 inhibitor

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专利权人:

PFIZER INC.

发明人:

Chekal, Brian Patrick,Ide, Nathan D.

申请号：

NZ71013814

公开号：

NZ710138A

申请日:

2014.02.08

申请国别(地区):

NZ

年份:

2020

代理人:

摘要：

This invention relates to the crystalline free base of acetyl-8- cyclopentyl-5-methyl-2-(5-piperazin-l-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one, formula (1) having large particle size to avoid agglomeration, to pharmaceutical compositions and dosage forms comprising the free base, and to methods for making and using such compounds, compositions and dosage forms in the treatment of cell proliferative diseases, such as cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/