Jun Won CHOI,Kyoungsun KIM,Si Young LEE,Tae Heum UM
申请号:
US15559865
公开号:
US20180280479A1
申请日:
2017.08.04
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to a stabilized external preparation comprising thymosin beta 4 (Tβ4) as an active ingredient. More specifically, the present invention relates to a therapeutically effective external preparation with improved stability and biological activity of Tβ4. The preparation according to the present invention provides Tβ4 in a stable state by maintaining the biological activity of Tβ4 and minimizing the generation of Tβ4 sulfoxide through oxidization reactions and multimers through aggregation.