REICHART, BRUNO,ABICHT, JAN-MICHAEL,MAYR, TANJA,LANGIN, MATTHIAS,BRENNER, PAOLO,WOLF, ECKHARD,KLYMIUK, NIKOLAI
申请号：
CA3095143
公开号：
CA3095143A1
申请日:
2019.03.29
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present invention relates to methods for prolonging the survival of a primate that is transplanted a genetically modified heart, kidney, lung or liver from a xenogeneic mammal in a life supporting technique, and to compositions for use in a method of prolonging the survival of a primate that has been transplanted a genetically modified heart, kidney, lung or liver from a xenogeneic mammal in a life supporting technique. The invention is also directed to a living primate, whose heart, kidney, lung or liver is functionally substituted by a transplanted, genetically modified heart, kidney, lung or liver, respectively, from a xenogeneic mammal. Finally, the invention is directed to a genetically modified mammal and a donor organism for xenogeneic organ transplants as well as to methods of producing same.
