The present invention provides a drug delivery devices (2,3 It 102) is the sequential administration of substance, including a first variable capacity reservoir (40a 140a) keep the first substance and include a first outlet (41 a, 141 a) with the first removable wall (43a 143a), the second variable volume reservoir (40b 140b) keep one second substance and including an escape way (41 b 141 b) and the second removable wall (43b 143b), one first wall startup structure (65a, 70a, 75a, 77a 177a) the first removable wall of the movement (43a activated 143a) to which by first outlet, (41 a expel the dosage of the first substance 141 a), one second wall startup structure (65b, 70b, 75b, 77b 177b) the second removable wall of the movement (43b activated 143b) to which by escape way, (41 b expel the dosage of the second substance 141 b) and a drive structure (90 190) for activating the first wall startup structure (65a, 70a, 75a, 77a 177a) and the second wall startup structure (65b, 70b, 75b, 77b 177b). Drive structure (90 190) predetermined movement is executed during a sequential administration of the first substance and the second substance, the movement of prede limitations includes that the mobile subsequent second part of first part is mobile, is configured to the first wall startup structure (65a, 70a, 75a, 77a of activation 177a) during first part is mobile and the second wall startup structure (65b, 70b, 75b, 77b of activation 177b) during second part is mobile.
