Thomas L. CHERPES,Nirk E. QUISPE CALLA,Rodolfo Daniel VICETTI MIGUEL
申请号:
US16317247
公开号:
US20190224298A1
申请日:
2017.07.13
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Disclosed herein are methods and platforms for increasing utility and efficacy of a cellular vaccine. Specifically, disclosed are steps that optimize ex vivo B cell expansion and boost host in vivo immunity. Also disclosed is a platform for enhancing effectiveness of antigen presentation and antigen-specific immune responses. Also disclosed is a method for enhancing effectiveness of APCs in a subject. Also disclosed are vaccines and kits based on the platform.