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PYRIDINYL- AND PYRAZINYL-METHYLOXY-ARYL DERIVATIVES USEFUL AS INHIBITORS OF SPLEEN TYROSINE KINASE (SYK)
专利权人:
Michael David Barker;David Matthew Wilson;Francis Louis Atkinson;John Liddle
发明人:
Francis Louis Atkinson,Michael David Barker,John Liddle,David Matthew Wilson
申请号:
US14004388
公开号:
US20140005177A1
申请日:
2012.03.08
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A compound of formula (I):or a salt thereof;which is an inhibitor of spleen tyrosine kinase (SYK) and therefore potentially of use in treating diseases resulting from inappropriate activation of mast cells, macrophages, and B-cells and related inflammatory responses and tissue damage, for instance inflammatory diseases and/or allergic conditions, in cancer therapy, specifically heme malignancies, and autoimmune conditions.
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