Scott Kirk Napper,Kenneth Jason Kindrachuk,Samuel Kwadwo Attah-Poku
申请号:
US12666229
公开号:
US09102754B2
申请日:
2008.06.27
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Compositions and methods are provided for modulating an immune response in a vertebrate subject. Compositions and methods can comprise administering a modified host defense peptide to the vertebrate subject in an amount effective to activate the immune response in the vertebrate subject, wherein the modified host defense peptide is inverted in amino acid sequence from an amino terminus to a carboxy terminus or modified to one or more D-amino acids, or both modifications, when compared to a host defense peptide. Compositions and methods are provided which comprise administering a modified host defense peptide to the vertebrate subject in an amount effective to modify an immune response in the vertebrate subject.