Prabha N. Ibrahim;Hanna Cho;Songyuan Shi;Wayne Spevak
发明人:
Prabha N. Ibrahim,Wayne Spevak,Hanna Cho,Songyuan Shi
申请号：
US12467208
公开号：
US08153641B2
申请日:
2009.05.15
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Compounds and salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof and uses thereof are described. In certain aspects and embodiments, the described compounds or salts thereof, formulations thereof, conjugates thereof derivatives thereof, forms thereof are active on at least one Raf protein kinase. Also described are methods of use thereof to treat diseases and conditions, including diseases and conditions associated with activity of Raf protein kinases, including melanoma, colorectal cancer, thyroid cancer, ovarian cancer, cholangiocarcinoma, pain or polycystic kidney disease.
