Souches productrices à forte teneur en acide eicosapentaénoique de Yarrowia lipolytique

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专利权人:

E. I. du Pont de Nemours and Company

发明人:

申请号：

EP13161757.3

公开号：

EP2649887A2

申请日:

2005.11.03

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

Engineered strains of the oleaginous yeast Yarrowia lipolytica capable of producing greater than 25% eicosapentaenoic acid (EPA, an (ω-3 polyunsaturated fatty acid) in the total oil fraction are described. These strains comprise various chimeric genes expressing heterologous desaturases, elongases and acyltransferases and optionally comprise various native desaturase and acyltransferase knockouts to enable synthesis and high accumulation of EPA. Production host cells are claimed, as are methods for producing EPA within said host cells.

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