Pyrimidine compounds having a novel dibenzylamine structure and pharmaceuticals containing the same

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专利权人:

興和株式会社

发明人:

扇谷 忠明,三浦 徹,奥田 歩,荒井 俊晴,山崎 浩市,青木 太郎,三代沢 勝利,柴田 治樹,渋谷 公幸

申请号：

JP2009510828

公开号：

JP5244095B2

申请日:

2008.04.10

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

A compound represented by the following general formula (I), wherein R 1 , R 2 , R 3 , R 4 and R 5 represent hydrogen atom, a halo(lower alkyl) group, cyano group and the like, R 6 represents an alkyl group, a cycloalkyl group and the like, R 7 , R 8 , R 9 and R 10 represent hydrogen atom, a halogen atom, a lower alkyl group, a halo(lower alkyl) group and the like, R 11 and R 12 represent hydrogen atom, a lower alkyl group, a (lower cycloalkyl)(lower alkyl) group and the like, and R 13 represents hydrogen atom, a halogen atom, a lower alkoxy group and the like, which has potent inhibitory activity on cholesterol ester transfer protein (CETP).

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