PEPTIDE DEFORMYLASE INHIBITORS

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专利权人:

GLAXOSMITHKLINE INTELLECTUAL PROPERTY (No.2)LIMITED

发明人:

AUBART,KELLY,MARSHALL,GILLIAN,JASON,MICHAEL,QIN,DONGHUI,MCKEOWN,ROBERT,RAHN,WILLIAMS,GLEENN,R

申请号：

ZA201404044

公开号：

ZA201404044B

申请日:

2014.06.03

申请国别(地区):

ZA

年份:

2015

代理人:

摘要：

The present invention relates to {2-(alkyl)-3-[2-(5-fluoro-4-pyrimidinyl)hydrazino]-3-oxopropyl}hydroxyformamide compounds of Formula (I): or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions, processes for making and use of such compounds in the inhibition of bacterial peptide deformylase (PDF) activity and in treatment methods for bacterial infections.

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