The invention provides compounds of the formula (I) wherein the variables are as defined in the specification. The compounds of the invention are inhibitors of metalloproteinase MMP-12 and are among other things useful for the treatment of obstructive airway diseases, such as chronic obstructive pulmonary disease (COPD).本發明提供式(I)的化合物:;其中變量如在說明書中定義的。;本發明的化合物為金屬蛋白酶MMP-12的抑制劑,其特別地用於治療阻塞性呼吸道疾病,例如慢性阻塞性肺病(COPD)。