The Trustees of the University of Pennsylvania;Inovio Pharmaceuticals, Inc.;David B. Weiner;Jian Yan
发明人:
David B. Weiner,Jian Yan
申请号:
US14910136
公开号:
US10398769B2
申请日:
2014.08.04
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Provided herein are nucleic acid sequences that encode novel consensus amino acid sequences of HA Influenza A of serotype H7N9 alone and in combination with HA hemagglutinin and/or influenza B hemagglutinin, as well as genetic constructs/vectors and vaccines expressing the sequences. Also provided herein are methods for generating an immune response against one or more influenza A serotypes and/or influenza B serotypes, or combinations thereof, using the vaccines that are provided.