Ethan Settembre,Angelica MEDINA-SELBY,Doris COIT,Philip R. DORMITZER
申请号:
US14946324
公开号:
US20160222066A1
申请日:
2015.11.19
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention relates to chimeric norovirus VP1 proteins containing the S-domain of VP1 of a first norovirus strain and a P-domain that contains at least a portion of the P-domain of VP1 of a second norovirus strain. The invention also relates to nucleic acids that encode the chimeric VP1 proteins, virus-like particles that contain a chimeric norovirus VP1 protein, and to immunogenic compositions