The present disclosure is directed to a container assembly including a container sealed by a closure. The container has a main chamber in which a highly nutritive liquid food product can be filled and stored aseptically or through retort processing. The closure includes a separate chamber in which a supplement sensitive to thermal processing of the liquid food product can be filled and stored. The container assembly permits the closure filled with the supplement to be attached to the container after severe thermal processing conditions have subsided, and permits the supplement to be conveniently and hygienically mixed with the liquid food product immediately prior to use.