A quick lock and release clamp mountable onto the bedrail of an operating table hospital bed and the like. The clamp includes a body a foot and a mouth having at least three sides defined by the body and foot. A biasing member is coupled to at least one of the body and the foot wherein an actuating member coupled to the biasing member is configured to transmit a force to the mouth via the biasing member. A protrusion extending from the body and towards the foot engages the bedrail thereby fixing the clamp onto the bedrail by moving the actuating member in a first direction.