Dae Jin KIM,Young Jin PARK,Sung Min BAE,Sung Youb JUNG,Se Chang KWON
申请号:
US15780934
公开号:
US20180360973A1
申请日:
2016.12.02
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to a protein conjugate in which a physiologically active polypeptide and a biocompatible material are linked through a fatty acid derivative, thus having an extended duration of physiological activity compared to that of a natural type, and a method of preparing the same. The protein conjugate of the present invention in which a biocompatible material, fatty acid, and a physiologically active polypeptide are linked was confirmed to have an increased half-life of the physiologically active polypeptide, and thus can be widely used in the field of protein drugs.