Ja Seong KOO;Chang Hee MIN;Sung Wuk KIM;Seong Choon CHOE;Soon Im LEE;Sang Ouk SUN;Na Young LEE
发明人:
Sung Wuk KIM,Seong Choon CHOE,Chang Hee MIN,Soon Im LEE,Ja Seong KOO,Sang Ouk SUN,Na Young LEE
申请号：
US13433000
公开号：
US20130158084A1
申请日:
2012.03.28
申请国别(地区):
US
年份:
2013
代理人:
摘要：
A pharmaceutical composition comprising losartan or a pharmaceutically acceptable salt thereof, which is capable of treating or preventing side effects such as muscle toxicity caused by administering a statin-based lipid-lowering drug, and a pharmaceutical combination composition comprising a statin drug and a losartan drug as active ingredients are provided. The pharmaceutical composition comprising losartan or a pharmaceutically acceptable salt thereof provides an effect on treating or preventing muscle-related side effects caused by administration of a statin drug for treating hyperlipidemia, as well as an intrinsic pharmacological effect for treating or preventing hypertension. When administered along with a statin drug in sequence or co-administered at the same time with the statin drug, the pharmaceutical composition can exhibit an effect of effectively or significantly decreasing or preventing side effects such as muscle toxicity.
