This invention relates generally to a use of a medicament to treatinflammatory bowel diseases (IBD), asthma, Crohn's Disease (CD), multiplesclerosis (MS), rheumatoid arthritis (RA), graft versus host disease (GVHD),host versus graft disease, and various spondyloarthropathies, comprisingadministering a steroid-sparing effective amount of an immunoglobulin or to apatient in need thereof. The invention also relates generally to combinationtherapies for the treatment of these conditions.