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Compositions, formulations and methods of bio-balancing the pH of sterile isotonic saline and hypertonic saline solutions
专利权人:
Pharmacaribe; LLC
发明人:
Warner, William Randolph,Gutmann, Werner
申请号:
AU2013384270
公开号:
AU2013384270A1
申请日:
2013.05.30
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
Compositions, formulations and methods bio-balance the pH of sterile, sodium chloride inhalation and pulmonary irrigation solutions, such that the solutions are bio-similar to the homeostatic pH state of the Human Airway Surface Liquid (ASL) at 7.4. These solutions are sterile, non-pyrogenic, additive and preservative free, and provided in sterile unit-of-use, blow-fill-seal vials. These solutions are intended for use in the induction of sputum production where sputum production is indicated, such as with Cystic Fibrosis patients and Bronchoalveolar lavage procedures. The solutions can be provided in concentrations from about 1.0 to about 10% sodium chloride in USP / Sterile water. The sodium chloride solutions are homogenous mixtures (complete solutions) that include sterile water, sodium chloride, and sodium bicarbonate as a buffer. The solutions are provided in saline concentrations from 0.045% to 10%, for example, concentrations of 0.9%, 3%, 3.5%, 6%, 7% with a pH of 7.4.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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