Compositions of PD-1 antagonists and methods of use

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专利权人:

Inc.;Amplimmune

发明人:

LANGERMAN, Solomon,LIU, Linda

申请号：

AU2013227994

公开号：

AU2013227994A1

申请日:

2013.09.10

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

#$%^&*AU2013227994A120130926.pdf#####H: fm Intrwovn NRPortbl DCC FMT 5446060_I.doc-5/09/2013 ABSTRACT Methods of treating cancer and infectious diseases utilizing a treatment regimen comprising administering a compound that reduces inhibitory signal transduction in T cells, in combination with a potentiating agent, such as cyclophosphamide, to product potent T cell mediated responses, as described. Compositions comprising the PD-1 antagonists and potentiating agents useful in the methods of the invention are also disclosed.

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