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Purine derivatives for use in the treatment of allergic, inflammatory and infectious diseases
专利权人:
GlaxoSmithKline LLC
发明人:
Keith Biggadike,Diane Mary Coe,Xiao Qing Lewell,Charlotte Jane Mitchell,Stephen Allan Smith,Naimisha Trivedi
申请号:
US14280115
公开号:
US09233962B2
申请日:
2014.05.16
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to compounds of formula (I):wherein R1 is C1-6alkylamino, C1-6alkoxy, or C3-7cycloalkyloxy; m is an integer having a value of 3 to 6; n is an integer having a value of 0 to 4; and salts thereof are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions for example allergic rhinitis and asthma, the treatment of infectious diseases and cancer, and may also be useful as vaccine adjuvants.
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