GOODMAN, MARK,TAYLOR, ROBERT W.,TAKEMIYA, KIYOKO,MURTHY, NIREN,MOHAMMAD, RAFI,NING, XINGHAI
申请号：
CA2961672
公开号：
CA2961672A1
申请日:
2015.09.21
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
This disclosure relates saccharide analogs such as thiomaltose-based analogs for targeting bacteria and related uses. In certain embodiments, the disclosure relates to methods of transferring a molecule of interest into bacteria comprising mixing bacteria with a non-naturally occurring conjugate, wherein the conjugate comprises a thiomaltose-based analog and a molecule of interest under conditions such that the conjugate is transported across the bacterial cell wall. In certain embodiments, the molecule of interest can be a tracer or an antibiotic.
