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Methods of Treating Autoimmune Diseases
专利权人:
GENZYME CORPORATION
发明人:
Johanne KAPLAN,John M. McPHERSON
申请号:
US13680667
公开号:
US20170165360A9
申请日:
2012.11.19
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Novel methods for treating patients with autoimmune diseases are disclosed. The methods of the invention include first depleting circulating lymphocytes in the mammal, e.g., by administering anti-thymocyte antibody, and then, during the course of repopulation, administering to the mammal a therapeutically effective amount of latent TGF-β and/or another agent that promotes expansion of regulatory T cells. In certain aspects, the disclosed process results in improved kidney function and survival rates.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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