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Oral dosage form comprising an antimisuse system
专利权人:
Florence Guimberteau
发明人:
Florence Guimberteau,Frederic Dargelas,Gérard Soula,Rémi Soula
申请号:
US11651577
公开号:
US08895063B2
申请日:
2007.01.10
申请国别(地区):
US
年份:
2014
代理人:
摘要:
An oral solid dosage form containing one or several active principle(s) having analgesic properties, the composition of said dosage form being such that it prevents the misuse of said dosage form through the liquid extraction of the active principle(s) contained therein, using commonly available solvents.Said oral solid dosage form containing at least one salt of at least one analgesic active principle, and an anti-misuse system comprising at least one quenching agent, said quenching agent being suitable for inducing complexation of said analgesic active principle salt when the analgesic active principle salt is improperly extracted, notably by a drug abuser, in vitro in solution from said oral solid dosage form.
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