There is disclosed compositions and methods relating to or derived from anti-LAG3 antibodies. More specifically, there is disclosed fully human antibodies that bind LAG3, LAG3-antibody binding fragments and derivatives of such antibodies, and LAG3-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating a disease.本發明揭示與抗LAG3抗體相關或衍生自其之組合物及方法。更特定而言，本發明揭示結合LAG3之全人類抗體、該等抗體之LAG3抗體結合片段及衍生物以及包含該等片段之LAG3結合多肽。另外，本發明揭示編碼該等抗體、抗體片段及衍生物及多肽之核酸，包含該等多核苷酸之細胞，製造該等抗體、抗體片段及衍生物及多肽之方法，及使用該等抗體、抗體片段及衍生物及多肽之方法，包括治療疾病之方法。
