SHTYRLIN JURIJ GRIGOREVICH,Штырлин Юрий Григорьевич,SHTYRLIN NIKITA VALEREVICH,Штырлин Никита Валерьевич,SAPOZHNIKOV SERGEJ VITALEVICH,Сапожников Сергей Витальевич,IKSANOVA ALFIJA GABDULAKHATOVNA,Икса
申请号：
RU2014137515/04
公开号：
RU0002561281C1
申请日:
2014.09.16
申请国别(地区):
RU
年份:
2015
代理人:
摘要：
FIELD: biotechnology.SUBSTANCE: the invention relates to novel derivatives of pyridoxine of general formula (I), having high antibacterial activity. , where at R1+R2 = -C(CH3)2-, R3+R4 = -CH2N+(C8H17)2CH2-, n = 1, X = Cl, m = 0, at R1 = R2 = 3, R3+R4 = -CH2N+(C8H17)2CH2-, n = 1, X = Cl, m = 1, at R1+R2 = -C(CH3)2-, R3 = R4 = CH2N+(CH3)2C8H17, n = 2, X = Cl, m = 0, at R1 = R2 = 3, R3+R4 = CH2N+(CH3)2C8H17, n = 2, X = Cl, m = 1, at R1+R2 = -C(CH3)2-, R3 = CH2OH, R4 = CH2N+(CH3)2C8H17, n = 1, X = Br, m = 0, at R1+R2 = -C(CH3)2-, R3 = CH2OH, R4 = CH2N+(CH3)2C18H37, n = 1, X = Br, m = 0, at R1 = R2 = H, R3 = CH2OH, R4 = CH2N+(CH3)2C8H17, n = 1, X = Br, m = 1, at R1 = R2 = H, R3 = CH2OH, R4 = CH2N+(CH3)2C18H37, n = 1, X = Br, m = 1, at R1+R2 = -C(CH3)2-, R3 = CH2N+(CH3)2C8H17, R4 = 3, n = 1, X = Cl, m = 0, at R1+R2 = -C(CH3)2-, R3 = CH2N+(CH3)2C18H37, R4 = 3, n = 1, X = Cl, m = 0, at R1 = R2 = R4 = H, R3 = CH2N+(CH3)2C8H17, n = 1, X = Cl, m = 1, at R1 = R2 = R4 = H, R3 = CH2N+(CH3)2C18H37, n = 1, X = Cl, m = 1. The invention may find application in human and veterinary medicine.EFFECT: increased efficiency of application of the compounds.2 cl, 1 tbl, 12 exИзобретение относится к новым производным пиридоксина общей формулы (I), обладающим высокой антибактериальной активностью.где при R1+R2=-С(СН3)2-, R3+R4=-CH2N+(C8H17)2CH2-, n=1, X=Cl, m=0,при R1=R2=Η, R3+R4=-CH2N+(C8H17)2CH2-, n=1, Χ=Cl, m=1,при R1+R2=-С(СН3)2-, R3=R4=CH2N+(CH3)2C8H17, n=2, Χ=Cl, m=0,при R1=R2=Η, R3+R4=CH2N+(CH3)2C8H17, n=2, X=Cl, m=1,при R1+R2=-C(CH3)2-, R3=CH2OH, R4=CH2N+(CH3)2C8H17, n=1, X=Br, m=0,при R1+R2=-C(CH3)2-, R3=CH2OH, R4=CH2N+(CH3)2C18H37, n=1, X=Br, m=0,при R1=R2=H, R3=CH2OH, R4=CH2N+(CH3)2C8H17, n=1, X=Br, m=1,при R1=R2=H, R3=CH2OH, R4=CH2N+(CH3)2C18H37, n=1, X=Br, m=1,при R1+R2=-C(CH3)2-, R3=CH2N+(CH3)2C8H17, R4=Η, n=1, X=Cl, m=0,при R1+R2=-C(CH3)2-, R3=CH2N+(CH3)2C18H37, R4=Η, n=1, X=Cl, m=0,при R1=R2=R4=H, R3=CH2N+(CH3)2C8H17, n=1, X=Cl, m=1,при R1=R2=R4=H, R3=CH2N+(CH3)2C18H37, n=1, X=
