#$%^&*AU2016228261A120170406.pdf#####ABSTRACT The invention relates to apparatus and methods for use in the delivery and deployment of a prosthetic mitral valve into a heart via a transatrial approach. The method comprising: inverting an outer frame of a prosthetic mitral valve when the prosthetic mitral valve is in a biased expanded configuration, the prosthetic mitral valve being formed with a shape-memory material； after the inverting, inserting the prosthetic mitral valve into a lumen of a delivery sheath such that the prosthetic mitral valve is moved to a collapsed configuration, while remaining inverted； inserting the delivery sheath through a transatrial entry site directly into a left atrium of a patient； moving the prosthetic mitral valve distally out of the lumen of the delivery sheath such that the inverted outer frame of the prosthetic mitral valve reverts and the prosthetic mitral valve assumes its biased expanded configuration； and positioning the prosthetic mitral valve within a mitral annulus of the heart.31/51 Atty Docket No. TNDY-035101WO 321861-2187 Dispose outer frame of prosthetic mitral 880 valve in inverted configuration Insert prosthetic mitral valve and tether 882 into lumen of delivery sheath Insert catheter through apex of heart and 884 position distal end of the catheter within left ventricle of the heart Insert delivery sheath with valve and tether into left atrium, through a native 886 mitral valve gap and position distal end of delivery sheath within left ventricle of heart Capture distal end portion of tether with , 88 snare and pull tether through catheter and out ventricle wall at apex of heart Deploy prosthetic mitral valve into left 890 atrium of heart such that mitral valve reverts and assumes biased expanded configuration Position prosthetic mitral valve in native 892 mitral annulus and secure epicardial pad to apex of heart FIG. 33
