The Board of Trustees of the Leland Stanford Junior University
发明人:
Garcia, Kenan Christopher,Levin, Aron
申请号:
AU2012211277
公开号:
AU2012211277A1
申请日:
2012.01.26
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Wnt compositions and methods for their use are provided. Compositions of the invention comprise fragments of wnt polypeptides having a desired biological activity, which fragments are referred to herein as "mini-wnts". These compositions and methods find particular use in determining bind to Wnt receptors; inhibiting Wnt signaling in a cell that expresses a Wnt receptor; in delivering a functional moiety to a cell that expresses a Wnt receptor; and as an immunogen for producing Wnt-specific antibodies.