A device to process and transport medical instruments in a protected manner comprises a containing body (14), in which to place a medical instrument (12), and a closing body (16), in which the containing body (14) and the closing body (16) are configured mobile with respect to each other, in order to define a hermetically closed condition and an open condition. The device comprises at least one sensor (30) configured to automatically detect a variation between the open condition and the hermetically closed condition and to transmit a corresponding signal, and an electronic state display (26) configured to receive the signal from the sensor (30) and to display toward the outside information regarding the current state associated specifically to the signal received.