Syed F. A. Hossainy,Gordon S. Stewart,Benjamyn Serna,Lothar W. Kleiner
申请号:
US13481515
公开号:
US08715707B2
申请日:
2012.05.25
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Methods are disclosed for controlling the morphology and the release-rate of active agent from a coating layer for medical devices comprising a polymer matrix and one or more active agents. The methods comprise exposing a wet or dry coating to a freeze-thaw cycle. The coating layer can be used for controlled delivery of an active agent or a combination of active agents.