DENNIS C. LIOTTA,MERRICK ALMOND,DARRYL CLEARY,JOSE SORIA,GEORGE R. PAINTER,MARCOS SZNAIDMAN
申请号:
BR9912951
公开号:
BR9912951B1
申请日:
1999.08.12
申请国别(地区):
BR
年份:
2012
代理人:
摘要:
Processes for the preparation of 1,3-oxathiolane nucleosides are provided that include efficient methods for the preparation of the 1,3-oxathiolane ring and subsequent condensation of the 1,3-oxathiolane with a pyrimidine or purine base. Using the processes described herein, the compounds can be provided as isolated enantiomers.