HENRY, Kevin,JARAMILLO, Maria Luz,MACKENZIE, Colin Roger,MARCIL, Anne
申请号:
SG11202002331Q
公开号:
SG11202002331QA
申请日:
2018.09.10
申请国别(地区):
SG
年份:
2020
代理人:
摘要:
AXL-specific antibodies and uses therefor are described, including monoclonal and single domain antibodies. Such antibodies bind to cell surface expressed human AXL at an epitope in an immunoglobulin-like (IgL) domain of the AXL ectodomain. The antibody may be used in an antibody-drug conjugate (ADC), for example in the treatment, detection or staging of cancer. The antibody may be biparatopic.