Yan Ni,Ayesha Sitlani,Shilpa Pandit,Dale Lewis,Xun Shen,Sharon Lobo,Timothy McCabe,Jon Condra,Rose Cubbon,Fubao Wang
申请号：
US13497663
公开号：
US20120219558A1
申请日:
2010.09.15
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Antagonists of human proprotein convertase subtilisin-kexin type 9 (PCSK9) are disclosed. Said antagonists are effective in the inhibition of PCSK9 function and thereby provide compositions of matter useful for the treatment of conditions associated with PCSK9 activity. The present invention further discloses nucleic acids encoding PCSK9 antagonists as well as methods of making and using PCSK9 antagonists.
