The discloser relates to use of compound A in combination with compound B for preparation of medicament for treating gout or hyperuricemia Specifically, compound A is selected from the compound of formula (I), or the medicinal salt thereof, or the ester thereof, and compound B is selected from the allopurinol and febuxostat. In particular, the combination of the compound of formula (I-1) with febuxostat in the treatment of gout or hyperuricemia has shown a good therapeutic effect.本公開涉及化合物A與化合物B聯合在製備治療痛風或高尿酸血症的藥物中的用途。具體而言，化合物A選自式(I)化合物、或其可藥用鹽、或其酯，化合物B選自別嘌呤醇、非布司他。尤其是式(I-1)化合物聯合非布司他治療痛風或高尿酸血症的方法，顯示了良好的治療效果。
