Liang DENG,Jedd WOLCHOK,Taha MERGHOUB,Stewart SHUMAN,Peihong DAI,Weiyi WANG
申请号：
US16741634
公开号：
US20200222479A1
申请日:
2020.01.13
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present disclosure relates to modified vaccinia Ankara (MVA) virus or MVAΔ；E3L delivered intratumorally or systemically as an anticancer immunotherapeutic agent, alone, or in combination with one or more immune checkpoint blocking agents for the treatment of malignant solid tumors. Particular embodiments relate to mobilizing the host's immune system to mount an immune response against the tumor.
