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Fluorescent Perylene Derivatives for Direct Detection of Heparin
专利权人:
Roland Kraemer
发明人:
Roland Kraemer,Helga Szelke,Job Harenberg,Armin Poeck
申请号:
US13390799
公开号:
US20120220617A1
申请日:
2010.08.19
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention relates to a perylene diimide derivative and to an in vitro method for preparing the same. In addition, the invention relates to a method for detecting heparin in a sample using perylene diimide derivatives, wherein the interaction of the perylene diimide derivative with heparin modulates the intensity of the fluorescent signal of the mixture compared to the solution. The invention also comprises a diagnostic kit for detecting heparin in a sample in vitro, comprising the perylene diimide derivative, as well as the use of the perylene diimide derivative for neutralizing the anticoagulant activity of heparin.
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