ABSTRACT - 598455 The disclosure relates to a compound represented by Formula (I) e.g. 7-[3-fluoro-4-({ [(2-fluoro-5-methylphenyl)amino]carbonyl} amino)phenoxy]thieno[3,2-b]pyridine-2-carboxylic acid, wherein the variables are as defined in the specification. These compounds are suitable for the treatment of one of the diseases or conditions selected from the group consisting of colorectal cancer, lung cancer, hematological cancer, renal cancer, liver cancer, breast cancer, diabetic retinopathy, macular degeneration, age-related macular degeneration, retinopathy of prematurity, ocular angiogenesis, retinal edema, retinal ischemia, diabetic macular edema, cystoid macular edema, retinal vein occlusion, branch vein occlusion, preretinal neovascularization, laserinduced choroidal neovascularization, neovascularization associated with keratoplasty, glaucoma and ocular tumors, arthritis, restenosis, hepatic cirrhosis, atherosclerosis, psoriasis, diabetes mellitus, wound healing, inflammation, neurodegenerative diseases and immune disorders.
