Inhibiteurs hétérobicycliques de la protéine kinase à anneau bicyclique substitué en 6,6

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专利权人:

OSI Pharmaceuticals; LLC

发明人:

申请号：

EP09156987.1

公开号：

EP2168968B1

申请日:

2005.03.31

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

Compounds of the formula (I) and pharmaceutically acceptable salts thereof, wherein X 1 , X 2 , X 3 , X 4 , X 5 , X 6 , X 7 , R 1 , and Q 1 are defined herein, inhibit the IGF-1R enzyme and are useful for the treatment and/or prevention of hyperproliferative diseases such as cancer, inflammation, psoriasis, allergy/asthma, disease and conditions of the immune system, disease and conditions of the central nervous system.

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