A combination of antioxidants is proposed as a supplement based on the best available clinical data. The present invention proposes a research-driven approach premised on the basic tenet that there are multiple antioxidant systems and various rate limiting steps. According to the present invention, specific combinations can influence the oxidative process in a way that cannot be achieved by any one individual molecule. It is an object of the present invention to develop and evaluate various combinations of antioxidants in order to determine which combinations are most effective in the treatment of specific conditions. It is a further object of the present invention to use clinical data to determine which combinations of antioxidants consistently yield clinically viable results.