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LIPID DERIVATIVE FOR NUCLEIC ACID INTRODUCTION
专利权人:
NIPPON FINE CHEMICAL CO., LTD.;SHIZUOKA PREFECTURAL UNIVERSITY CORPORATION
发明人:
Tomohiro ASAI,Naoto OKU,Noriyuki MAEDA,Naofumi FUKATA,Koji TOMITA
申请号:
US16604298
公开号:
US20200031853A1
申请日:
2018.03.01
申请国别(地区):
US
年份:
2020
代理人:
摘要:
An object is to provide a lipid particle that is not positively charged at a pH of the body fluid (typically in the neutral range), and that enables efficient onset of the effect of a medicinal substance encapsulated in the lipid particle; and to provide a lipid for forming the lipid particle. The object is achieved by the phospholipid represented by formula (1), and a lipid particle containing the phospholipid:wherein R1 and R2 are identical or different, and represent a chain hydrocarbon group, m represents 1 or 2, n represents 1 or 2, and p represents an integer of 1 to 4.
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