ARMSTRONG, DONNA J.,HU, ESSA H.,KELLY, MICHAEL J. III,LAYTON, MARK E.,LI, YIWEI,LIANG, JUN,RODZINAK, KEVIN J.,ROSSI, MICHAEL A.,SANDERSON, PHILIP E.,WANG, JIABING
申请号:
PL06772406
公开号:
PL1898903T3
申请日:
2006.06.07
申请国别(地区):
PL
年份:
2013
代理人:
摘要:
The instant invention provides for substituted naphthyridine compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.