The invention refers to polypeptides combining novel human CD3 antigens and their preparation and use in the treatment and / or diagnosis of various diseases, as well as double antibody molecules that can activate immune injection cells and be used for diagnosis and / or treatment. 5. The present invention related to new human CD3 antien binding polymers and their preparation and use in the treatment and / or diagnosis of variable diseases, and also related to specific anti body movements capable of activating immediate effector cells and their use in diagnosis and / or treatment of variable diseasesLa presente invención hace referencia a polipéptidos de unión al antígeno CD3 humano novedosos y su preparación y uso en el tratamiento y/o diagnóstico de diversas enfermedades, y también hace referencia a moléculas de anticuerpos biespecíficos capaces de activar células efectoras inmunitarias y su uso en el diagnóstico y/o tratamiento de diversas enfermedades.The present invention relates to novel human CD3 antigen-binding polypeptides and their preparation and use in the treatment and/or diagnosis of various diseases, and also relates to bispecific antibody molecules capable of activating immune effector cells and their use in diagnosis and/or treatment of various diseases.